220663-25-2Relevant academic research and scientific papers
Chiral macrocyclic polyethers incorporating a tetraoxaspiro [5.5]undecane or trioxa, azaspiro [5.5]undecane moiety
Garcia, Christophe,Pointud, Yvon,Jeminet, Georges,Dugat, Denise,Beltran, Jose Luis
, p. 4253 - 4265 (1998)
New macrocyclic polyethers possessing chirality due to a spiro ring junction are prepared from 2,8-dihydroxymethylated (+)- 1,4,7,10- tetraoxaspiro[5.5]undecane 1 and (+)- 1,4,7-trioxa- 10-azaspiro[5.5]undecane 2, both (E,E). N-Functionalization of compounds derived from 2 is also examined. The complexing properties of representative ligands 3, 4, 5 measured by spectrophotometry in THF, for alkaline and alkaline-earth cations, indicate that these spheric positively-charged species are weakly associated.
