220697-90-5

Basic information

• Product Name: (-)-(3aS)-eseroline-4'-benzyloxyphenylcarbamate
• Synonyms: (-)-(3aS)-eseroline-4'-benzyloxyphenylcarbamate
• CAS NO: 220697-90-5
• Molecular Weight: 443.546
• Mol File: 220697-90-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (-)-(3aS)-eseroline-4'-benzyloxyphenylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-(3aS)-eseroline-4'-benzyloxyphenylcarbamate(220697-90-5)
• EPA Substance Registry System: (-)-(3aS)-eseroline-4'-benzyloxyphenylcarbamate(220697-90-5)

Safety Data

• Hazardous Substances Data: 220697-90-5(Hazardous Substances Data)

Upstream product

• 51388-20-6 4-benzyloxyaniline hydrochloride 
• 50528-73-9 4-benzyloxy-phenyl isocyanate 
• 469-22-7 eseroline 

Relevant articles and documents

4'-Hydroxyphenylcarbamates of (3aS)eseroline and (3aS)-N(1)- noreseroline: Potential metabolites of the Alzheimer's anticholinesterase drug phenserine

4'-Hydroxyphenylcarbamates of (3aS)-eseroline (3) and (3aS)-N(1)- noreseroline (4), as predicted metabolites of phenserine (1), were synthesized. Biological evaluation showed that 3 and 4 possessed potent activities for inhibition of acetylcholinesterase and butyrylcholinesterase in vitro. In contrast the intermediates, 4'-benzyloxyphenserine (8) and 4'- benzyloxy N(1)-benzylphenserine (12), demonstrated unusually potent and selective activities against butyrylcholinesterase.