220734-61-2Relevant academic research and scientific papers
Synthetic trisaccharides reveal discrimination of: Endo -glycosidic linkages by exo -acting α-1,2-mannosidases in the endoplasmic reticulum
Nitta, Kyohei,Kuribara, Taiki,Totani, Kiichiro
supporting information, p. 4137 - 4145 (2021/05/19)
A tri-antennary Man9GlcNAc2 glycan on the surface of endoplasmic reticulum (ER) glycoproteins functions as a glycoprotein secretion or degradation signal after regioselective cleavage of the terminal α-1,2-mannose residue of each branch. Four α-1,2-mannos
Sequential one-pot glycosidations catalytically promoted: Unprecedented strategy in oligosaccharide synthesis for the straightforward assemblage of the antitumor PI-88 pentasaccharide
Valerio, Silvia,Pastore, Antonello,Adinolfi, Matteo,Iadonisi, Alfonso
, p. 4496 - 4503 (2008/09/21)
(Chemical Equation Presented) The pentasaccharide sequence of the most active components of the antitumor drug PI-88, currently in phase II clinical trial, has been rapidly assembled in high overall yield and in only three steps starting from three monosa
Synthesis of the glycosyl phosphatidyl inositol anchor of rat brain thy- 1
Tailler, Denis,Ferrieres, Vincent,Pekari, Klaus,Schmidt, Richard R.
, p. 679 - 682 (2007/10/03)
Disintegration of the target molecule 1 into building blocks A-E was performed. For D, an efficient synthesis of mannose derivative 5, representing mannose residue c in the target molecule, could be performed; 5 permits the required regioselective access
