220757-98-2

Upstream product

• 930-68-7 cyclohexenone 
• 1121-18-2 2-methyl-2-cyclohexen-1-one 
• 873-55-2 sodium benzenesulfonate 
• 583-60-8 2-Methylcyclohexanone 
• 65979-78-4 2-Methyl-2-phenylselanyl-cyclohexanone 
• 19980-35-9 1-trimethylsilyloxy-2-methyl-1-cyclohexene 

Downstream Products

• 220758-00-9 1,1-(ethylenedioxy)-2-methyl-3-(phenylsulfonyl)-cyclohexane 
• 220758-02-1 1,1-(ethylenedioxy)-3-(10-hydroxydecyl)-2-methyl-3-(phenylsulfonyl)-cyclohexane 

Relevant academic research and scientific papers

Preventive and/or Therapeutic Agent for Diabetic Vascular Disorder and Respiratory Disorder

The present invention provides preventive and/or therapeutic agents for either one, or both, of a diabetic vascular disorder and a diabetic respiratory disorder comprising, as an active ingredient, a cyclohexenone long chain alcohol compound represented b

THERAPEUTIC AGENT FOR SENSORY ABNORMALITY

The present invention provides therapeutic agents for sensory disorders represented by the following formula (1): [wherein R1, R2, and R3 each represent a hydrogen atom or a methyl group, and X represents a linear or branc

Cyclohexenone long-chain alcohol and medicament containing same

Described is a cyclohexenone long-chain alcohol represented by the formula (1): wherein R1, R2 and R3 each independently represents a hydrogen atom or a methyl group and X represents a C10-18 alkylene or alkenylene group. The cyclohexanone long-chain alco

Cyclohexenonic long-chain fatty alcohols as neuronal growth stimulators

Neurotrophic factors play an important role in the development and maintenance of neurons, thus providing a suitable therapeutic approach for the treatment of neurodegenerative diseases. However, their clinical use has revealed problematic because of a number of technical and biological disadvantages. Among the different strategies proposed to overcome such difficulties, the search for non-peptide substances with neurotrophic potential is giving promising results. Here we will expose major findings in this field, drawing special attention to cyclohexenonic long-chain fatty alcohols, a novel family of compounds that promote neuronal survival and neurite outgrowth.

Effect of cyclohexenonic long chain fatty alcohols on neurite outgrowth. Study on structure-activity relationship

Four series of long chain fatty alcohols bearing a cyclohexenone moiety in addition to a ω-alkanol side chain were synthesized using 'Umpolung' reactivity strategy. Their effect on neurite outgrowth was evaluated by means of fetal rat neurons in culture. The length of the ω-hydroxy side chain is a crucial factor for biological activity.