220835-39-2

Upstream product

• 220835-24-5 5-(4-chloro-phenyl)-7-(4-iodo-phenyl)-3,7-dihydro-pyrrolo[2,3-d]pyrimidin-4-one 
• 220835-25-6 4-chloro-7-(4-methoxyphenyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidine 

Downstream Products

• 220835-47-2 [5-(4-chloro-phenyl)-7-(4-iodo-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-hydrazine 
• 220835-57-4 9-(4-chloro-phenyl)-7-(4-iodo-phenyl)-7H-pyrrolo[3,2-e]tetrazolo[1,5-c]pyrimidine 

Relevant academic research and scientific papers

Synthesis of 7H-tetrazolo[1,5-c]pyrrolo[3,2-e]pyrimidines and their reductive ring cleavage to 4-aminopyrrolo[2,3-d]pyrimidines

Some new 7,9-disubstituted 7H-1,2,3,4-tetrazolo[1,5-c]pyrrolo[3,2- e]pyrimidines 5 have been synthesized either by diazotization of 4-hydrazino- 5,7-disubstituted-7H-pyrrolo[2,3-d]pyrimidines 4 obtained by hydrazinolysis of 4-chloro-5,7-disubstituted-7H-pyrrolo[2,3-d]pyrimidines 3 or via a substitution reaction between 3 and sodium azide. 5,7-Disubstituted-7H- pyrrolo[2,3-d]pyrimidin-4(3H)-ones 2 were obtained by cyclocondensation of 2- amino-3-cyano-1,4-disubstituted pyrroles 1 with formic acid which on chlorination using phosphorus oxychloride afforded 3. A novel route for the synthesis of 4-amino-5,7-disubstituted-7H-pyrrolo[2,3-d]pyrimidines 6 by the reductive ring cleavage of 5 has been reported.