220866-33-1

Upstream product

• 91-40-7 2-(phenylamino)benzoic acid 
• 64675-79-2 ethyl [4-hydroxy-2-oxo-1-phenyl-1,2-dihydro-3-quinoline]carboxylate 

Downstream Products

• 220865-86-1 4-benzylamino-2-oxo-1-phenyl-1,2-dihydro-quinoline-3-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

TUMOR NECROSIS FACTOR ALPHA INHIBITORS AND THEIR USE IN THE TREATMENT OF HUMAN DISEASES

treatment of a variety of disorders, including the treatment of pathological conditions associated with tumor necrosis factor alpha. The inhibitors of tumor necrosis factor alpha have the following structures: including stereoisomers, pharmaceutically acceptable salts, and solvates thereof, wherein substituents are as defined herein. Compositions containing an inhibitor of tumor necrosis factor alpha in combination with a pharmaceutically acceptable carrier are also provided, as well as methods for use of the same.

4-Hydroxyquinol-2-ones. 86. Synthesis of methyl (ethyl) esters of 1-substituted 4-amino-2-oxoquinoline-3-carboxylic acids

Several variants of the synthesis of esters of 1-N-substituted 4-amino-2-oxoquinoline-3-carboxylic acids have been studied, one of which is recommended as preparative. 2005 Springer Science+Business Media, Inc.