220904-17-6

Basic information

• Product Name: 2-BroMo-5-(1,3-dioxolan-2-yl)pyridine
• Synonyms: 2-BroMo-5-(1,3-dioxolan-2-yl)pyridine;2-BroMo-5-[1,3]dioxolan-2-yl-pyridine
• CAS NO: 220904-17-6
• Molecular Formula: C₈H₈BrNO₂
• Molecular Weight: 230
• Mol File: 220904-17-6.mol
• Article Data: 15

Chemical Properties

• Appearance: /
• Density: 1.593±0.06 g/cm3 (20 ºC 760 Torr)
• CAS DataBase Reference: 2-BroMo-5-(1,3-dioxolan-2-yl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BroMo-5-(1,3-dioxolan-2-yl)pyridine(220904-17-6)
• EPA Substance Registry System: 2-BroMo-5-(1,3-dioxolan-2-yl)pyridine(220904-17-6)

Safety Data

• Hazardous Substances Data: 220904-17-6(Hazardous Substances Data)

Usage

General Description

2-Bromo-5-(1,3-dioxolan-2-yl)pyridine is a chemical compound with the molecular formula C7H7BrNO2. It is a pyridine derivative containing a bromine atom and a 1,3-dioxolane ring. 2-BroMo-5-(1,3-dioxolan-2-yl)pyridine is commonly used in organic synthesis and pharmaceutical research as a building block for the synthesis of various biologically active molecules. It is also used as a reagent in the preparation of heterocyclic compounds. Additionally, 2-Bromo-5-(1,3-dioxolan-2-yl)pyridine has been investigated for its potential anti-inflammatory and anti-tumor properties, showing promising results in preliminary studies. However, further research is needed to fully understand its potential applications and mechanisms of action.

Upstream product

• 624-28-2 2,5-dibromopyridine 
• 174608-37-8 2-bromo-5-(dimethoxymethyl)pyridine 
• 107-21-1 ethylene glycol 
• 149806-06-4 6-bromonicotinaldehyde 

Downstream Products

• 671776-91-3 5-(1,3-dioxolan-2-yl)-2-cyano-pyridine 
• 1123838-17-4 x 
• 1342828-76-5 1-Cyclopropyl-3-(2,3-difluoro-4-(2-(5-formylpyridin-2-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)urea 
• 1342836-68-3 4-(2-(5-(1,3-Dioxolan-2-yl)pyridin-2-yl)thieno[3,2-b]pyridin-7-yloxy)-2,3-difluoroaniline 
• 1342836-73-0 1-(4-(2-(5-(1,3-Dioxolan-2-yl)pyridin-2-yl)thieno[3,2-b]pyridin-7-yloxy)-2,3-difluorophenyl)-3-cyclopropylurea 
• 179873-48-4 2,2’-bipyridine-5-carbaldehyde 
• 131747-68-7 2-cyanopyridine-5-carboxyaldehyde 
• 1292309-87-5 C₂₁H₂₇NO₈S 

Relevant articles and documents

Practical acetalization and transacetalization of carbonyl compounds catalyzed by recyclable PVP-I

A novel PVP-I catalyzed acetalizations/transacetalizations of carbonyl compounds has been developed processing with a mild and easy handling fashion. Different types of Acyclic and cyclic acetals were prepared from carbonyl compounds or their acetals successfully. Further applications of newly developed catalytic combination were testified. This protocol featured with simplicity of operation, mild reaction condition, short reaction time, recyclable of catalyst and broad substrates scope with excellent yields.

Tandem vinyl radical Minisci-type annulation on pyridines: one-pot expeditious access to azaindenones

A new regiospecific alkylative/alkenylative cascade annulation of pyridines has been achieved whilst the corresponding classic Minisci alkylative annulation failed. This protocol provides a novel and expeditious access to azaindenones and related compoundsviacross-dehydrogenative coupling with the long-standing problem of C2/C4 regioselectivity of pyridines being well addressed.

Spin-dimer networks: Engineering tools to adjust the magnetic interactions in biradicals

Magneto-structural correlations in stable organic biradicals have been studied on the example of weakly exchange coupled models with nitronyl nitroxide and imino nitroxide spin-carrying entities. Here, heteroatom substituted 2,2′-diaza- and 3,3′-diaza-tolane bridged biradicals were compared with the hydrocarbon analogue, while a biphenyl model with its 2,2′-bipyridine counterpart. For a 3,3′-diazatolane bridge the torsional angle between the nitronyl nitroxides and the pyridyl rings increased heavily (～52-54°) leading to a smaller theoretical intra-dimer exchange coupling value. However, a very large antiferromagnetic coupling was obtained experimentally. This could be appropriately explained by the presence of dominating inter-dimer exchange between the molecules. For the bis(imino nitroxide) with tolane bridge a field induced ordered state between 1.8 to 4.3 T in AC-susceptibility measurements was observed. In terms of a Bose Einstein condensate (BEC) of triplons this phenomenon could be described as a magnetic field induced ordered phase with 3D character.