220968-18-3Relevant academic research and scientific papers
Synthesis and biological evaluation of novel heterocyclic ionone-like derivatives as anti-inflammatory agents
Balbi, Alessandro,Anzaldi, Maria,Mazzei, Mauro,Miele, Mariangela,Bertolotto, Maria,Ottonello, Luciano,Dallegri, Franco
, p. 5152 - 5160 (2006)
Five- and six-membered heterocyclic ionone-like derivatives 4-6 have been synthesised in one step and with good yield from the key intermediate 3a and appropriate bifunctional reagents. Four were active as inhibitors of the respiratory burst of human neut
Synthesis of new heterocyclic derivatives of retinoids
Sottofattori, Enzo,Anzaldi, Maria,Balbi, Alessandro
, p. 1377 - 1380 (1998)
Reaction of α- and β-ionones 1 and 2 with dialkylformamide/phosphorus oxychloride affords enamines 6 and 7 along with the expected chloro derivatives 4 and 5. Reaction of 6a with hydrazines, hydroxylamine and guanidine furnished pyrazoles, isoxazole, pyri
