221020-91-3

Upstream product

• 221020-89-9 O-(2,3,4-tri-O-benzyl-β-L-idopyranosyl)-(1->1)-2,3,4-tri-O-benzyl-β-L-idopyranoside 
• 81105-73-9 2,2',3,3',4,4'-hexa-O-benzyl-6,6'-dideoxy-6,6'-diiodo-trehalose 
• 221020-88-8 O-(2,3,4-tri-O-benzyl-6-deoxy-α-D-xylo-hex-5-enopyranosyl)-(1->1)-2,3,4-tri-O-benzyl-6-deoxy-α-D-xylo-hex-5-enopyranoside 
• 81105-71-7 2,3,4,2',3',4'-hexa-O-benzyl-6,6'-di-O-p-tolylsulfonyl-α,α-trehalose 

Downstream Products

• 221020-92-4 methyl 1)-2,3,4-tri-O-benzyl-β-L-idopyranosid>uronate 

Relevant academic research and scientific papers

Novel synthesis of L-iduronic acid using trehalose as the disaccharidic starting material

For the preparation of L-iduronic acid, trehalose was converted into a derivative of a novel disaccharide, β-L-idopyranosyl β-L-idopyranoside, through diastereoselective hydroboration of the 5,5'-di-eno intermediate. The 6- and 6'-hydroxy groups were then oxidized in two steps to give a disaccharide composed of 2 units of L-iduronate moieties, which underwent acidic cleavage of the glycosidic bond to give the target compound.