221050-76-6

Basic information

• Product Name: 1-AMino-7-isoquinolineMethanol
• Synonyms: 1-AMino-7-isoquinolineMethanol;(1-AMinoisoquinolin-7-yl)Methanol
• CAS NO: 221050-76-6
• Molecular Formula: C10H10N2O
• Molecular Weight: 174.1992
• Mol File: 221050-76-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-AMino-7-isoquinolineMethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-AMino-7-isoquinolineMethanol(221050-76-6)
• EPA Substance Registry System: 1-AMino-7-isoquinolineMethanol(221050-76-6)

Safety Data

• Hazardous Substances Data: 221050-76-6(Hazardous Substances Data)

Usage

General Description

1-Amino-7-isoquinolinemethanol, also known as 7-IQAM, is a chemical compound with the molecular formula C10H10N2O. It is an amino alcohol that contains both an amine and a hydroxyl group. 1-AMino-7-isoquinolineMethanol is commonly used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. It has also been studied for its potential biological activity, including its role as a potential anti-cancer agent. 7-IQAM has a unique structure that makes it a valuable building block for the production of various complex organic molecules. Its versatile chemical properties and potential biological functions make it a significant compound in the field of pharmaceutical and medicinal chemistry.

InChI:InChI=1S/C10H10N2O/c11-10-9-5-7(6-13)1-2-8(9)3-4-12-10/h1-5,13H,6H2,(H2,11,12)

Relevant articles and documents

1-amino-7-isoquinoline derivatives as serine protease inhibitors

The invention relates to serine protease inhibitor compounds of fornula (I) where R1is hydrogen, halo, cyano, nitro or hydroxyl, amino, alkoxy, alkyl amminoalkyl, hydroxyalkyl, thiol, alkylthio, aminosulphonyl alkoxyalkyl, alkoxycarbonyl, acyloxymethoxycabonyl or alkylamino optionally substituted by hydroxy, alkylamino, alkoxy, oxo, aryl, cycloalkyl, amino, halo, cyano, nitro, thiol, alkylthio, alkylsulphonyl, alkylsulphenyl, alkylsulphonamido, alkylaminosulphonyl, haloalkoxy and haloalkyl; R2is hydrogen, halo, methyl amino, hydroxy, or oxo; and R is X—X—Y(R7)—L—Lp(D)n; wheren each X independently is a C, N, O or S atom or a CO, CR1, C(R1)2or NR1group, at least one X being C, CO, CR1or a C(R1)2group; Y (the α-atom) is a nitrogen atom or a CR1group or Y and L taken together form a cyclic group; R7is a lipophilic group selected from alkyl, alkenyl, mono- or bi-cycloalkyl, aryl, heteroaryl, mono- or bicycloalkylalkyl, mono- or bicycloalkylakenyl, aralkyl, heteroaryl-alkyl, arylalkenyl, heteroarylalkenyl all optionally substituted by a group R1; L is an organic linker group containing 1 to 5 backbone atoms selected from C, N, O and S, or a branched alkyl or cyclic group; Lp is a lipophilic organic group selected from alkyl, heterocyclic, alkenyl, alkaryl cycloalkyl, polycycloalkyl, cycloalkenyl, aryl, aralkyl or haloalkyl group or a combination of two or more such groups optionally substituted by one or more of oxa, thia, aza or R1groups; D is a hydrogen bond donor group; and n is 0, 1 or 2 and salts thereof.