221050-89-1

Basic information

• Product Name: tert-Butyl 4-(pyriMidin-4-yl)piperazine-1-carboxylate
• Synonyms: tert-Butyl 4-(pyriMidin-4-yl)piperazine-1-carboxylate
• CAS NO: 221050-89-1
• Molecular Formula: C13H20N4O2
• Molecular Weight: 264.3235
• Mol File: 221050-89-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: tert-Butyl 4-(pyriMidin-4-yl)piperazine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-Butyl 4-(pyriMidin-4-yl)piperazine-1-carboxylate(221050-89-1)
• EPA Substance Registry System: tert-Butyl 4-(pyriMidin-4-yl)piperazine-1-carboxylate(221050-89-1)

Safety Data

• Hazardous Substances Data: 221050-89-1(Hazardous Substances Data)

Usage

General Description

Tert-Butyl 4-(pyrimidin-4-yl)piperazine-1-carboxylate is a chemical compound belonging to the family of piperazines. These are organic compounds that contain a piperazine ring, a six-membered ring with two nitrogen atoms and four carbon atoms. Specifically, this compound has a carboxylate ester group (CO2R), which is part of a larger piperazine structure substituted by a tert-butyl and a pyrimidine ring. Pyrimidines are aromatic heterocyclic organic compounds consisting of two nitrogen atoms, which contribute to their biological activities, such as acting as vital components of nucleic acid. The molecular formula of this compound is C14H23N5O2. Its specific properties, uses and toxicity level will depend on its synthetic method and any additional molecular modifications.

Upstream product

• 3934-20-1 2,6-Dichloropyrimidine 
• 96042-30-7 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran 
• 57260-71-6 1-t-Butoxycarbonylpiperazine 

Relevant articles and documents

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The invention relates to serine protease inhibitor compounds of fornula (I) where R1is hydrogen, halo, cyano, nitro or hydroxyl, amino, alkoxy, alkyl amminoalkyl, hydroxyalkyl, thiol, alkylthio, aminosulphonyl alkoxyalkyl, alkoxycarbonyl, acyloxymethoxycabonyl or alkylamino optionally substituted by hydroxy, alkylamino, alkoxy, oxo, aryl, cycloalkyl, amino, halo, cyano, nitro, thiol, alkylthio, alkylsulphonyl, alkylsulphenyl, alkylsulphonamido, alkylaminosulphonyl, haloalkoxy and haloalkyl; R2is hydrogen, halo, methyl amino, hydroxy, or oxo; and R is X—X—Y(R7)—L—Lp(D)n; wheren each X independently is a C, N, O or S atom or a CO, CR1, C(R1)2or NR1group, at least one X being C, CO, CR1or a C(R1)2group; Y (the α-atom) is a nitrogen atom or a CR1group or Y and L taken together form a cyclic group; R7is a lipophilic group selected from alkyl, alkenyl, mono- or bi-cycloalkyl, aryl, heteroaryl, mono- or bicycloalkylalkyl, mono- or bicycloalkylakenyl, aralkyl, heteroaryl-alkyl, arylalkenyl, heteroarylalkenyl all optionally substituted by a group R1; L is an organic linker group containing 1 to 5 backbone atoms selected from C, N, O and S, or a branched alkyl or cyclic group; Lp is a lipophilic organic group selected from alkyl, heterocyclic, alkenyl, alkaryl cycloalkyl, polycycloalkyl, cycloalkenyl, aryl, aralkyl or haloalkyl group or a combination of two or more such groups optionally substituted by one or more of oxa, thia, aza or R1groups; D is a hydrogen bond donor group; and n is 0, 1 or 2 and salts thereof.