22108-99-2Relevant academic research and scientific papers
PHENANTHRENE DERIVATIVES FOR USE AS MEDICAMENTS
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, (2016/08/07)
The present invention refers to phenanthrene derivatives for use as medicaments, mainly in the prevention and/or treatment of Myotonic Dystrophy Type 1, Huntington's Disease Like 2, Spinocerebellar Ataxia Type 8, Myotonic Dystrophy Type 2, Spinocerebellar Ataxia Type 3, Fragile-X-Associated Tremor/Ataxia Syndrome, Frontotemporal Degeneration/Amyotrophic Lateral Sclerosis and Spinocerebellar Ataxia Type 31. In a preferred embodiment, phenanthrene derivatives of the invention are also used as antimyotonic agents. Therefore, this invention may be included either in the whole pharmaceutical or medical field.
HOFMANN ELIMINATION WITH DIAZOMETHANE ON QUATERNARY BENZYLTETRAHYDROISOQUINOLINE RELATED ALKALOIDS
Lu, Sheng-Teh,Tsai, Ian-Lih
, p. 751 - 768 (2007/10/02)
The investigation have been made to the reaction of a large excess of diazomethane on the quaternary benzyltetrahydroisoquinoline related alkaloids, aporphines, benzyltetrahydroisoquinolines, pavines and protopine.From the structural elucidation of the reaction products, it has been found that the first and second Hofmann elimination proceeded.
