221100-93-2Relevant academic research and scientific papers
Click inspired novel pyrazole-triazole-persulfonimide & pyrazole-triazole-aryl derivatives; Design, synthesis, DPP-4 inhibitor with potential anti-diabetic agents
Nidhar, Manisha,Khanam, Shaziya,Sonker, Priyanka,Gupta, Priya,Mahapatra, Archisman,Patil, Swaraj,Yadav, Brijesh Kumar,Singh, Rahul Kumar,Kumar Tewari, Ashish
supporting information, (2022/01/22)
This work presented the first report on designing, synthesizing of novel pyrazole-triazole-persulfonimide (7a-i) and pyrazole-triazole-aryl derivatives (8a-j) via click reaction using CuI catalyst and evaluated for their anti-diabetic activity and DPP-4 i
Rh(II)-catalyzed asymmetric cyclopropenation of propargyl derivatives; synthesis of cyclopropene- and cis-cyclopropane-amino acids
Mueller, Paul,Imogai, Hassan
, p. 4419 - 4428 (2007/10/03)
The [Rh2{(2S)-mepy}4]-catalyzed cyclopropenation of propargylamines carrying two carboxyl or sulfonyl protecting groups with ethyl diazoacetate proceeds in high yield and with enantioselectivities in the range of 90→97% ee. Selective deprotection of the TEOC-derivative afforded ethyl 2- aminomethylcycloprop-2-ene-1-carboxylate which was converted to several analogs of γ-aminobutyric acid (GABA) containing the cyclopropene or cyclopropane ring.
