221121-41-1Relevant academic research and scientific papers
Synthesis of Novel Chiral Benzophospholanes and Their Application in Asymmetric Hydrogenation
Shimizu, Hideo,Saito, Takao,Kumobayashi, Hidenori
, p. 185 - 189 (2007/10/03)
A new class of chiral ligands bearing one or two benzophospholanes was developed for the purpose of Ru-catalyzed asymmetric hydrogenation. Although results of the Ru catalysis remain insufficient so far, 1,2-bis(2-isopropyl-2,3- dihydro-1H-phosphindol-1-yl)benzene (iPr-BeePHOS: 2b) has been found to provide high enantioselectivity in the Rh-catalyzed asymmetric hydrogenation of an enamide.
