221163-63-9Relevant academic research and scientific papers
Design, synthesis, and AMPA receptor antagonistic activity of a novel 6-nitro-3-oxoquinoxaline-2-carboxylic acid with a substituted phenyl group at the 7 position
Takano, Yasuo,Shiga, Futoshi,Asano, Jun,Ando, Naoki,Uchiki, Hideharu,Fukuchi, Kazunori,Anraku, Tsuyosi
, p. 5841 - 5863 (2007/10/03)
We describe the design, synthesis, and biological properties of a novel series of 7-substituted 6-nitro-3-oxoquinoxaline-2-carboxylic acids. After designing, studying the structure-activity relationships, and evaluating the properties of various compounds
6,7-asymmetrically disubstituted quinoxalinecarboxylic acid derivatives, addition salts thereof, and processes for the preparation of both
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Page column 41, (2010/11/30)
The present invention provides 6,7-asymmetrically disubstituted quinoxalinecarboxylic acid compounds and their addition salts, and processes for preparing them, which have antagonism against excitatory amino acid receptors, in particular, an AMPA receptor
