Welcome to LookChem.com Sign In|Join Free

CAS

  • or

221177-51-1

Post Buying Request

221177-51-1 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

221177-51-1 Usage

Chemical Properties

Off-white Solid

Uses

Intermediate in the preparation of dihydrobenzoxazepinones as HIV reverse transcriptase inhibitors.

Check Digit Verification of cas no

The CAS Registry Mumber 221177-51-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,1,1,7 and 7 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 221177-51:
(8*2)+(7*2)+(6*1)+(5*1)+(4*7)+(3*7)+(2*5)+(1*1)=101
101 % 10 = 1
So 221177-51-1 is a valid CAS Registry Number.

221177-51-1Downstream Products

221177-51-1Relevant articles and documents

4,1-Benzoxazepinone analogues of efavirenz (Sustiva) as HIV-1 reverse transcriptase inhibitors

Cocuzza, Anthony J.,Chidester, Dennis R.,Cordova, Beverly C.,Klabe, Ronald M.,Jeffrey, Susan,Diamond, Sharon,Weigelt, Carolyn A.,Ko, Soo S.,Bacheler, Lee T.,Erickson-Viitanen, Susan K.,Rodgers, James D.

, p. 1389 - 1392 (2007/10/03)

A series of 4,1-benzoxazepinone analogues of efavirenz (Sustiva) as potent NNRTIs has been discovered. The cis-3-alkylbenzoxazepinones are more potent then the trans isomers and can be synthesized preferentially by a novel stereoselective cyclization. The best compounds are potent orally bioavailable inhibitors of both wild-type HIV-1 and its clinically relevant K103N mutant virus, but are highly protein-bound in human plasma.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 221177-51-1