221192-72-9Relevant academic research and scientific papers
Precursor directed biosynthesis of novel 6-deoxyerythronolide B analogs containing non-natural oxygen substituents and reactive functionalities
Hunziker, Daniel,Wu, Nicholas,Kenoshita, Kenji,Cane, David E.,Khosla, Chaitan
, p. 635 - 638 (2007/10/03)
Feeding of synthetic precursors to a blocked mutant of 6- deoxyerythronolide B synthase (DEBS) [1] led to production of novel 6- deoxyerythronolide B analogs in vivo containing additional non-natural oxygen substituents as well as additional reactive groups.
