221198-59-0

Upstream product

• 109-86-4 2-methoxy-ethanol 
• 369-34-6 3,4-difluoronitrobenzene 
• 403-19-0 2-fluoro-4-nitrophenol 
• 6482-24-2 2-Bromoethyl methyl ether 
• 22510-08-3 2-fluoro-5-nitrophenol 

Downstream Products

• 221199-26-4 3-fluoro-4-(2-methoxyethoxy)aniline 
• 1402581-25-2 1-[[5-tert-butyl-2-(3-chlorophenyl)-2H-pyrazol-3-yl]methyl]-3-[3-fluoro-4-(2-methoxyethoxy)phenyl]urea 
• 1402581-26-3 1-[[2-(3-chlorophenyl)-5-(trifluoromethyl)-2H-pyrazol-3-yl]methyl]-3-[3-fluoro-4-(2-methoxyethoxy)phenyl]urea 
• 1402586-81-5 phenyl 3-fluoro-4-(2-methoxyethoxy)phenylcarbamate 

Relevant academic research and scientific papers

HETEROCYCLIC COMPOUNDS AND USES THEREOF

The present invention relates to pharmaceutical compounds, compositions and methods, especially as they are related to compositions and methods for the treatment and/or prevention of a proliferation disorder, a cancer, a tumor, an inflammatory disease, an autoimmune disease, psoriasis, dry eye or an immunologically related disease, and in some embodiments diseases or disorders related to the dysregulation of kinase such as, but not limited to, EGFR (including HER), Alk, PDGFR, BLK, BMX/ETK, FLT3(D835Y), ITK, TEC, TXK, BTK, or JAK, and the respective pathways.

SUBSTITUTED PYRAZOLYL-BASED CARBOXAMIDE AND UREA DERIVATIVES BEARING A PHENYL MOIETY SUBSTITUTED WITH AN O-CONTAINING GROUP AS VANILLOID RECEPTOR LIGANDS

The invention relates to substituted pyrazolyl-based carboxamide and urea derivatives of formula (Q) as vanilloid receptor ligands, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.

2-Pyrimidinyl Pyrazolopyridine Erbb Kinase Inhibitors

The present invention provides 2-pyrimidinyl pyrazolopyridine compounds, compositions containing the same, as well as processes for the preparation and their use as pharmaceutical agents.

Process for the preparation of 7-substituted-3 quinolinecarbonitriles

There is provided a process for the preparation of 7-substituted-3-quinolinecarbonitriles and intermediates useful in a process to prepare 7-substituted-3-quinolinecarbonitriles and pharmaceutically acceptable salts is described. Where 7-fluoro-4-oxo-1,4-

THIOCARBAMIC ACID DERIVATIVES

Thiocarbamic acid derivatives represented by the following general formula or salts thereof which are useful as antibacterial agents: wherein R1 represents an alkyl group which may be substituted, or a cycloalkyl group which may be substituted; and R2, R3, and R4 independently represent hydrogen atom, a halogen atom, an alkyl group which may be substituted, an alkogyl group which may be substituted, an amino group which may be substituted, an alkanoyl group which may be substituted, a cycloalkyloxy group which has a heteroatom as a ring constituting atom and which may be substituted, or a saturated heterocyclic group which may be substituted; or any two of R2, R3, and R4 may bind to each other to form, together with the benzene ring, a condensed hydrocarbon ring which may be substituted.