22133-02-4Relevant articles and documents
Rhodium(iii)-catalyzed cascade C-H functionalization/annulation of sulfoximines with iodonium ylides for the synthesis of cyclohexanone-1,2-benzothiazines
Chen, Lu,Hao, Liqiang,Ji, Yafei,Wang, Yangyang,Wang, Zhichao,Wu, Gaorong,Xu, Xiaobo
supporting information, p. 887 - 894 (2022/02/03)
A highly efficient Rh(iii)-catalyzed cascade C-H activation/annulation of sulfoximines with iodonium ylides under metal-oxidant-free conditions has been reported. The fused cyclohexanone-1,2-benzothiazine scaffold is readily achieved with a one-pot proces
ALKYNYLPYRIMIDINES AS TIE2 KINASE INHIBITORS
-
Page/Page column 85, (2009/01/23)
The invention relates to alkynylpyrimidines according to the general formula (I) in which A, R1, R2, R3, R4, R5, and R6 are as defined in the claims, to pharmaceutical compositions comprising said alkynylpyrimidines, to methods of preparing said alkynylpyrimidines, as well as to uses thereof for manufacturing a pharmaceutical composition for the treatment of diseases of dysregulated vascular growth or of diseases which are accompanied with dysregulated vascular growth, wherein the compounds effectively interfere with Tie2 and VEGFR2 signalling.
Sulfoximine-substituted pyrimidines, processes for production thereof and use thereof as drugs
-
Page/Page column 55, (2010/11/28)
The invention relates to sulfoximine-substituted pyrimidines of the general formula I processes for the preparation thereof and their use as drugs.