221333-10-4

Upstream product

• 108-24-7 acetic anhydride 
• 221333-06-8 (S)-N-<2-<3,5-dimethoxy-2-<<(4-methoxyphenyl)methyl>thio>phenyl>-1-(hydroxymethyl)ethyl>-4-methoxybenzeneacetamide 
• 4693-91-8 4-methoxyphenyl-acetic chloride 
• 221332-90-7 N-<(4-methoxyphenyl)acetyl>-3,5-dimethoxy-2-<<(4-methoxyphenyl)methyl>thio>-L-phenylalanine methyl ester 
• 174905-91-0 3,5-dimethoxy-2-<<(4-methoxyphenyl)methyl>thio>-L-phenylalanine methyl ester 

Downstream Products

• 221333-40-0 (5S,10aS)-9-<<5-<(2S-trans)-2,5-dihydro-3,6-dimethoxy-2-(1-methylethyl)pyrazin-5-yl>methyl-1-methyl-1H-imidazol-4-yl>thio>-6,8-dimethoxy-5-<(4-methoxyphenyl)methyl>-1,5,10,10a-tetrahydroxazolo<3,4-b>isoquinolin-3(3H)-one 
• 221333-46-6 (5S,10aS)-9-<<5-<(2S-cis)-2,5-dihydro-3,6-dimethoxy-2-(1-methylethyl)pyrazin-5-yl>methyl-1-methyl-1H-imidazol-4-yl>thio>-6,8-dimethoxy-5-<(4-methoxyphenyl)methyl>-1,5,10,10a-tetrahydroxazolo<3,4-b>isoquinolin-3(3H)-one 
• 221332-83-8 (5S,10aS)-5-<<6,8-dimethoxy-5-<(4-methoxyphenyl)methyl>-3(3H)-oxo-1,5,10,10a-tetrahydroxazolo<3,4-b>isoquinolin-9-yl>thio>-3-methyl-D-histidine methyl ester 
• 221333-26-2 (5S,10aS)-6,8-dimethoxy-9-<(5-hydroxymethyl-1-methyl-1H-imidazol-4-yl)thio>-5-<(4-methoxyphenyl)methyl>-1,5,10,10a-tetrahydroxazolo<3,4-b>isoquinolin-3(3H)-one 
• 221333-22-8 (5S,10aS)-6,8-dimethoxy-9-<(5-formyl-1-methyl-1H-imidazol-4-yl)thio>-5-<(4-methoxyphenyl)methyl>-1,5,10,10a-tetrahydroxazolo<3,4-b>isoquinolin-3(3H)-one 
• 221333-15-9 (5S,10aS)-6,8-dimethoxy-5-<(4-methoxyphenyl)methyl>-9-<<(4-methoxyphenyl)methyl>thio>-1,5,10,10a-tetrahydroxazolo<3,4-b>isoquinolin-3(3H)-one 
• 221333-02-4 (1S,3S)-6,8-dimethoxy-3-hydroxymethyl-1-<(4-methoxyphenyl)methyl>-5-<<(4-methoxyphenyl)methyl>thio>-1,2,3,4-tetrahydroisoquinoline 
• 221333-19-3 (5S,10aS)-6,8-dimethoxy-9-mercapto-5-<(4-methoxyphenyl)methyl>-1,5,10,10a-tetrahydroxazolo<3,4-b>isoquinolin-3(3H)-one 
• 221333-12-6 (1S,3S)-3-acetyloxymethyl-6,8-dimethoxy-1-<(4-methoxyphenyl)methyl>-5-<<(4-methoxyphenyl)methyl>thio>-1,2,3,4-tetrahydroisoquinoline 

Relevant academic research and scientific papers

Synthetic studies on the starfish alkaloid imbricatine. Construction of an ent-imbricatine framework

A chiral synthetic route to the amino esters 5 and 6, which contain the fundamental framework of ent-imbricatine (ent-3), has been developed as a prelude to the total synthesis of the starfish alkaloid imbricatine (3). The route started from the sulfur-co