22134-11-8

Basic information

• Product Name: 2,4,6-TRIBROMOPHENYL ISOTHIOCYANATE
• Synonyms: 1,3,5-Tribromo-2-isothiocyanatobenzene;2,4,6-TRIBROMOPHENYL ISOTHIOCYANATE;2,4,6-TRIBROMOPHENYL ISOTHIOCYANATE 96%;2,4,6-Tribromophenyl isothiocyate, 98%
• CAS NO: 22134-11-8
• Molecular Formula: C₇H₂Br₃NS
• Molecular Weight: 371.87
• Mol File: 22134-11-8.mol
• Article Data: 1

Chemical Properties

• Melting Point: 106 °C
• Boiling Point: 380.1 °C at 760 mmHg
• Flash Point: 183.7 °C
• Appearance: /
• Density: 2.21 g/cm³
• Vapor Pressure: 1.22E-05mmHg at 25°C
• Refractive Index: 1.706
• CAS DataBase Reference: 2,4,6-TRIBROMOPHENYL ISOTHIOCYANATE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,6-TRIBROMOPHENYL ISOTHIOCYANATE(22134-11-8)
• EPA Substance Registry System: 2,4,6-TRIBROMOPHENYL ISOTHIOCYANATE(22134-11-8)

Safety Data

• Statements: R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.; R36/37/38:Irritating to eyes, respiratory system
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S36/37/39:Wear suitabl
• HazardClass: IRRITANT-HARMFUL
• Hazardous Substances Data: 22134-11-8(Hazardous Substances Data)

Usage

Uses

2,4,6-Tribromophenyl Isothiocyanate is used in preparation of the thiazole derivative compound and their pharmaceutical application.

InChI:InChI=1/C7H2Br3NS/c8-4-1-5(9)7(11-3-12)6(10)2-4/h1-2H

Upstream product

• 147-82-0 2,4,6-tribromoaniline 

Relevant articles and documents

Novel thiazole derivative compound as well as preparation method, pharmaceutical composition and pharmaceutical application of novel thiazole derivative compound

The invention belongs to the field of pharmaceutical and chemical industries and relates to a compound as shown in a general formula I, a pharmaceutical salt or a hydrate of the compound, a preparation method of the compound as shown in the general formula I, a pharmaceutical composition containing the compound as shown in the general formula I or the pharmaceutical salt or the hydrate of the compound and an application of the compound as shown in the general formula I or the pharmaceutical salt or the hydrate of the compound in production of drugs, wherein the compound as shown in the generalformula I has an effect on inhibiting a PI3K/Akt/mTOR signal pathway of a mammal, all substituent groups in the general formula I are defined as the specification, and the drugs are used for treatingdiseases caused by abnormal expression of the PI3K/Akt/mTOR signal pathway of the mammal.