22137-56-0

Upstream product

• 56177-37-8 1-(4-nitrophenyl)-2-(p-tolylsulfonyloxy)ethanone 
• 62-53-3 aniline 
• 100-19-6 (4-nitrophenyl)ethanone 
• 118985-14-1 p-nitrophenacyl m-nitrobenzenesulphonate 
• 118985-13-0 p-nitrophenacyl p-chlorobenzenesulphonate 
• 115400-13-0 p-nitrophenacyl benzenesulphonate 
• 99-81-0 4-Nitrophenacyl bromide 

Downstream Products

• 62761-46-0 5-(4-nitro-phenyl)-3-phenyl-3H-oxazol-2-one 
• 97814-19-2 1-phenyl-4-(4-nitrophenyl)imidazole 
• 1225051-19-3 (R)-1-(4-nitrophenyl)-2-(phenylamino)ethanol 
• 22108-58-3 ethyl 2-methyl-4-(4-nitrophenyl)-1-phenyl-1H-pyrrole-3-carboxylate 
• 88502-20-9 2-Methyl-5-(4-nitro-phenyl)-1-phenyl-1H-pyrrole-3-carboxylic acid ethyl ester 
• 35746-41-9 N-Acetyl-N-(4'-nitrophenacyl)-anilin 
• 78474-75-6 1-(4-amino-phenyl)-2-anilino-ethanone 

Relevant academic research and scientific papers

Synthesis of (Z)-nitroalkene derivatives through oxidative dehydrogenation coupling of α-aminocarbonyl compounds with nitromethane by copper catalysis

A novel copper-catalyzed cross-dehydrogenative coupling reaction of α-amino carbonyl compounds with nitromethane to synthesis of (Z)-nitroalkene derivatives has been established. (Z)-Nitroalkene derivatives are achieved through the cleavage of sp3 CsbndH bonds and formation of CsbndC double bond, with mild reaction conditions and excellent stereoselectivity.

One-Pot Metal-Free Cascade Synthesis of 2-(Perfluoroalkyl)pyrroles

An efficient synthesis of 2-(perfluoroalkyl)pyrroles that employs a sequential one-pot three-component reaction between substituted ω-bromoacetophenones, anilines, and methyl perfluoroalk-2-ynoates has been developed. This transition-metal-free cascade pr

Synthesis of optically active β-amino alcohols by asymmetric transfer hydrogenation of α-amino ketones

A number of optically active amino alcohols were synthesized by direct asymmetric transfer hydrogenation of the corresponding amino ketones with good-to-high enantiomeric excesses (up to 95%) and excellent yields (up to 93%). When the range of substrates was broadened to include α-sulfonamido ketones or α-keto sulfones, the corresponding products were obtained with 100% enantiomeric excesses. The absolute configuration of (1R)-2-[(4- chlorophenyl) amino]-1-(4-methoxyphenyl) ethanol was confirmed by X-ray crystal structure analysis. Georg Thieme Verlag Stuttgart.

Hypervalent iodine mediated syntheses of heterocycles: One-pot facile syntheses of 1,4-diaryl-2-mercaptoimidazoles, 2-(α-anilinoacetyl)thiophenes and 1-aryl-2-mercapto-4-(2-thienyl)imidazoles from aryl/2-thienyl methyl ketones

Successive treatment of acetophenones (1a-e) or 2-acetylthiophene (4) with benzene, appropriate aniline and KSCN/AcOH leads to the formation of 1,4-diaryl-2-mercaptoimidazoles (3aa-3ea) or 1-aryl-2-mercapto-4-(2-thienyl)imidazoles (6a-f) respectively.This procedure also provides 2(α-anilinoacetyl)thiophenes (5a-f) in one pot from 4.

Nucleophilic Substitution Reactions of Phenacyl Benzenesulphonates with Anilines in Methanol-Acetonitrile Mixtures

The nucleophilic substitution reactions of phenacyl benzenesulphonates with anilines in methanol-acetonitrile have been studied.A stronger nucleophile was found to cause less bond cleavage, while a better leaving group led to less bond formation, in compl

The Color of N-(4-Nitrophenacyl)arylamines

The N-(4-nitrophenacyl)arylamines 5, prepared from the arylamines 3 and 4-nitrophenacyl bromide (2), have a yellow, red or violet color, depending on the nature of the aryl substituents.The color is explained by intramolecular interaction of the electron accepting nitrobenzoyl group and the electron donating arylamine part of the molecules.On acetylation of the amino group the color is lost.There are no indications for an equilibrium between the amines 5 and N-(4-nitrostyryl)-arylamines 7.