22144-87-2

Upstream product

• 108-24-7 acetic anhydride 
• 23782-37-8 (3E)-3-benzylidene-1,3-dihydro-2H-indol-2-one 

Downstream Products

• 22144-90-7 6-acetyl-11-phenyl-4a-pyrrolidin-1-yl-1,2,3,4,4a,6,11,11a-octahydro-chromeno[2,3-b]indole 
• 15295-79-1 9-acetyl-2-ethoxy-4-phenyl-2,3,4,9-tetrahydro-pyrano[2,3-b]indole 
• 22144-88-3 9-acetyl-3-methyl-4-phenyl-2-piperidin-1-yl-2,3,4,9-tetrahydro-pyrano[2,3-b]indole 
• 1210071-96-7 ethyl 1'-acetyl-4-hydroxy-6-(4-methoxyphenyl)-2'-oxo-2-phenylspiro[cyclohex[3]ene-1,3'-indoline]-3-carboxylate 
• 1210071-97-8 ethyl 1'-acetyl-4-hydroxy-2'-oxo-2-phenyl-6-p-tolylspiro[cyclohex[3]ene-1,3'-indoline]-3-carboxylate 
• 1210071-98-9 ethyl 1'-acetyl-6-(4-bromophenyl)-4-hydroxy-2'-oxo-2-phenylspiro[cyclohex[3]ene-1,3'-indoline]-3-carboxylate 
• 1210071-95-6 ethyl 1'-acetyl-4-hydroxy-2'-oxo-2-phenyl-6-propylspiro[cyclohex[3]ene-1,3'-indoline]-3-carboxylate 
• 1210071-99-0 ethyl 1'-acetyl-4-hydroxy-6-(4-nitrophenyl)-2'-oxo-2-phenylspiro[cyclohex[3]ene-1,3'-indoline]-3-carboxylate 
• 1210071-72-9 ethyl 1'-acetyl-4-hydroxy-2'-oxo-2,6-diphenylspiro[cyclohex[3]ene-1,3'-indoline]-3-carboxylate 
• 1416431-99-6 C₂₃H₁₅NO₂ 
• 1259283-47-0 ethyl 1'-acetyl-2'-oxo-5-phenylspiro[cyclopent[2]ene-1,3'-indoline]-2-carboxylate 

Relevant academic research and scientific papers

Catalytic, enantioselective 1,3-dipolar cycloadditions of nitrile imines with methyleneindolinones

Catalytic, enantioselective 1,3-dipolar cycloadditions of nitrile imines with methyleneindolinones are reported. The spiro[pyrazolin-3,3′-oxindole] products are formed in good yields (up to 98%) and high enantioselectivity (up to 99% ee).