22145-26-2

Upstream product

• 217792-89-7 (8R,9S,13S,14S,17S)-3,17-bis(methoxymethoxy)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-2-ol 
• 113680-55-0 (8R,9S,13S,14S,17S)-3,17-bis(methoxymethoxy)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene 
• 1356544-07-4 2-O-benzyloxyestradiol-3,17β-O,O-bis(methoxymethyl)ether 
• 38781-50-9 2-(17β-acetoxy-2-hydroxy-estra-1,3,5(10)-trien-3-yloxy)-5-nitro-benzophenone 
• 100-44-7 benzyl chloride 
• 176219-90-2 (17β)-17-acetoxy-3-(2'-benzoyl-4'-nitrophenyloxy)-2-benzyloxy-1,3,5(10)-estratriene 

Downstream Products

• 1356544-11-0 2-O-benzyloxyestradiol-3,17β-O,O-bissulfamate 
• 1356544-08-5 2-O-benzyloxyestradiol-3,17β-O,O-bis(N-trutyl)sulfamate 
• 1356544-09-6 2-hydroxyestradiol-3,17β-O,O-bis(N-trityl)sulfamate 
• 176219-98-0 Acetic acid (8R,9S,13R,14S,15S,16S,17S)-16,17-diacetoxy-2,3-bis-benzyloxy-14-hydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-15-yl ester 
• 176219-97-9 Acetic acid (8R,9S,13R,14S,15R,16R,17S)-16,17-diacetoxy-2,3-bis-benzyloxy-14-hydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-15-yl ester 
• 176220-00-1 (8R,9S,13R,14S,15S,16S,17S)-2,3-Bis-benzyloxy-13-methyl-6,7,8,9,11,12,13,15,16,17-decahydro-cyclopenta[a]phenanthrene-14,15,16,17-tetraol 
• 176219-99-1 (8R,9S,13R,14S,15R,16R,17S)-2,3-Bis-benzyloxy-13-methyl-6,7,8,9,11,12,13,15,16,17-decahydro-cyclopenta[a]phenanthrene-14,15,16,17-tetraol 
• 176219-94-6 (8R,9S,13S,14S)-2,3-Bis-benzyloxy-14-hydroxy-13-methyl-6,7,8,9,11,12,13,14-octahydro-cyclopenta[a]phenanthren-17-one 
• 176219-95-7 (8R,9S,13R,14S,17R)-2,3-Bis-benzyloxy-13-methyl-6,7,8,9,11,12,13,17-octahydro-cyclopenta[a]phenanthrene-14,17-diol 
• 176219-92-4 (8R,9S,13S,14S)-2,3-Bis-benzyloxy-13-methyl-6,7,8,9,11,12,13,14-octahydro-cyclopenta[a]phenanthren-17-one 
• 176219-89-9 (14β,15α,16α,17α)-1,3,5(10)-estratriene-2,3,14,15,16,17-hexaol 
• 176219-89-9 (14β,15β,16β,17α)-1,3,5(10)-estratriene-2,3,14,15,16,17-hexaol 
• 176219-91-3 ((8R,9S,13S,14S)-2,3-Bis-benzyloxy-13-methyl-7,8,9,11,12,13,14,15-octahydro-6H-cyclopenta[a]phenanthren-17-yloxy)-triethyl-silane 
• 176219-93-5 (8R,9S,13S)-2,3-Bis-benzyloxy-13-methyl-6,7,8,9,11,12,13,16-octahydro-cyclopenta[a]phenanthren-17-one 

Relevant academic research and scientific papers

Synthesis and in vitro evaluation of 2-[11C]methoxyestradiol-3, 17β-O,O-bissulfamate for in vivo studies of angiogenesis

In the present study, 2-methoxyestradiol-3,17β-O,O-bissulfamate (1), a known angiogenesis inhibitor, was prepared in a radiolabeled form by 11C-methylation of 2-hydroxyestradiol-3,17β-O,O-bis(N-trityl) sulfamate (6) followed by detritylation. S

Syntheses of (14β,15β,16β,17α)- and (14β,15α,16α,17α)-1,3,5(10)-Estratriene-2,3,14,15, 16,17-hexaols, Possible Candidates for the Inagami-Tamura Endogenous Digitalis-like Factor, and Their Activity

Structures are proposed for the Inagami-Tamura endogenous digitalis-like factor (EDLF), and two possible candidates, (14β,15β,16β,17α)- and (14β,15α,16α,17α)-2,3,14,15,16,17-hexahydroxy-1,3,5(10)- estratrienes, were synthesized. Both compounds were potent in inducing a contractile response in isolated rat aorta and guinea pig left atrium.

Glycosides of catechol estrogens

There are described novel glycosides of catechol estrogen, a method of preparing the same, and a medicament comprising one of the glycosides as an active ingredient. The glycosides are shown by the formula of STR1 wherein X is carbonyl group or STR2 R10 is hydroxyl group or glycosyloxy group, and R2 is a hydrogen atom or ethynyl group; R11 is a hydrogen atom, hydroxyl group, or glycosyloxy group; R12 is hydroxyl group or glycosyloxy group; and R13 is hydroxyl group or glycosyloxy group, in which glycosyloxy group is selected from the group consisting of glucosyloxy, galactosyloxy, mannosyloxy, arabinosyloxy, ribosyloxy, xylosyloxy, fructosyloxy, rhamnosyloxy, fucosyloxy, maltosyloxy, cellobiosyloxy, lactosyloxy, sucrosyloxy, maltotriosyloxy, maltotetraosyloxy, maltopentaosyloxy, maltohexaosyloxy, maltoheptaosyloxy, and sialosyloxy, and in this case, at least one of R10, R11, R12, and R13 is glycosyloxy group as defined above.