221462-08-4Relevant articles and documents
Bicyclic analogues of inositol 1,4,5-trisphosphate based upon adenophostin A
Riley, Andrew M.,Potter, Barry V. L.
, p. 2213 - 2216 (1999)
The synthesis from myo-inositol of two bicyclic fused ring analogues of 1D-myo-inositol 1,4,5-trisphosphate in optically active form is described. The route demonstrates the application of the recently described butane-2,3- diacetal (BDA) protecting group
Bicyclic analogues of D-myo-inositol 1,4,5-trisphosphate related to adenophostin a: Synthesis and biological activity
Riley,Correa,Mahon,Taylor,Potter
, p. 2108 - 2117 (2007/10/03)
The high affinity of adenophostin A for 1D-myo-inositol 1,4,5-trisphosphate [Ins(1,4,5)P3] receptors may be related to an alteration in the position of its 2′-phosphate group relative to the corresponding 1-phosphate group in Ins(1,4,5)P3