22149-59-3

Usage

Uses

Used in Pharmaceutical Industry:
(17S,20R)-Pregna-5-ene-3β,11α,12β,14β,20-pentol is utilized as a precursor in the synthesis of various steroid hormones for pharmaceutical applications. Its role in hormone regulation makes it valuable for developing treatments related to hormonal imbalances and other conditions influenced by steroid hormones.
Used in Research Applications:
In the field of medical and biological research, (17S,20R)-Pregna-5-ene-3β,11α,12β,14β,20-pentol is employed as a research tool to study the mechanisms of steroid hormone synthesis and action. Its involvement in biological processes such as metabolism, inflammation, and immune function provides insights into the development of potential therapeutic agents targeting these pathways.
Used in Diagnostic Applications:
(17S,20R)-Pregna-5-ene-3β,11α,12β,14β,20-pentol may be used in diagnostic assays to evaluate the function of enzymes involved in steroid hormone synthesis. Its presence and levels can indicate the activity of these enzymes, which can be useful in the diagnosis and monitoring of certain endocrine disorders.

Upstream product

• 77524-37-9 tenasogenin 
• 98683-83-1 Dregeoside D_p1 
• 98665-65-7 Dregoside D_a1 

Relevant academic research and scientific papers

Polyhydroxy pregnanes from Dregea volubilis

Three new polyhydroxy pregnanes named dregealol (1), volubilogenone (2) and volubilol (3) were isolated from the flowers of Dregea volubilis, and their structures elucidated from extensive 2D NMR analysis. The structure of volubilol (3) was confirmed by X

TENASOGENIN, A PREGNANE ESTER FROM MARSDENIA TENACISSIMA

A new polyhydroxy pregnane ester named tenasogenin was isolated from the seeds of Marsdenia tenacissima.On the basis of chemical and spectroscopic evidence and identification of its hydrolysis products, its structure has been established as 11α-O-β,β-dimethylacryloyl-3β,12β,14β,20R-tetrahydroxypregn-5-ene.Key Word Index: Marsdenia tenacissima; Asclepiadaceae; tenasogenin; steroid; polyhydroxy pregnane ester.

Polyoxypregnane glycosides from the flowers of Dregea volubilis

Three novel polyoxypregnane glycosides, volubiloside A, B and C (1-3), were isolated from the flowers of Dregea volubilis Linn., and their structures were elucidated as drevogenin D-3-O-β-D-glucopyranosyl (1→4)-6-deoxy-3-O-methyl-β-D-allopyranosyl (1→4)-β-D-cymaropyranosyl (1→4)-β-D-cymaropyranoside, drevogenin D-3-O-β-D-glucopyranosyl (1→4)-6-deoxy-3-O-methyl-β-D-allopyranosyl (1→4)-β-D-cymaropyranosyl (1→4)-β-D-digitoxopyranoside and drevogenin P-3-O-β-D-glucopyranosyl (1→4)-6-deoxy-3-O-methyl-β-D-allopyranosyl (1→4)-β-D-cymaropyranosyl (1→4)-β-D-cymaropyranoside, respectively, on the basis of extensive NMR experiments, MALDI-TOF MS, and some chemical strategies.