221532-98-5

Upstream product

• 221532-97-4 2,2,2-trifluoro-N-{4-[1-(N-tert-butoxycarbonyl)piperidin-4-ylmethyl]-phenyl}acetamide 
• 27692-74-6 4-(4-aminobenzyl)pyridine 
• 313240-11-8 2,2,2-trifluoro-N-(4-(pyridin-4-ylmethyl)phenyl)acetamide 

Downstream Products

• 221532-96-3 4-(4-aminobenzyl)piperidine-1-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

As inhibitor and dichloropyridazine NAMPT polypyridine deriv.

Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.

NAMPT INHIBITORS

Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.

NAMPT INHIBITORS

Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.

2-(substituted-phenyl)amino-imidazoline derivatives

This invention relates to IP receptor antagonists selected from the group of compounds represented by Formula I: where:R1 is a group represented by formula (A), (B) or (C); and other substituents as defined in the specification, and their pharmaceutically acceptable salts or crystal forms thereof; and pharmaceutical compositions containing them; and methods for their use as therapeutic agents.