221545-53-5Relevant academic research and scientific papers
Mono- and bivalent ligands bearing mannose 6-phosphate (M6P) surrogates: Targeting the M6P/ insulin-like growth factor II receptor
Berkowitz, David B.,Maiti, Gourhari,Charette, Bradley D.,Dreis, Christine D.,MacDonald, Richard G.
, p. 4921 - 4924 (2004)
(Chemical Equation Presented) Mannose 6-phosphate mimics locked into the α-configuration and bearing hydrolase-resistant phosphate surrogates were synthesized and evaluated for binding affinity to the mannose 6-phosphate/insulin-like growth factor II rece
Facile installation of the phosphonate and (α,α- difluoromethyl)phosphonate functionalities equipped with benzyl protection
Berkowitz,Bhuniya,Peris
, p. 1869 - 1872 (2007/10/03)
Under appropriate conditions, dibenzyl (lithiomethyl)phosphonate and dibenzyl (lithiodifluoromethyl)phosphonate displace primary triflates to provide convenient access to the corresponding phosphonates, carrying benzyl ester protecting groups. This approa
