22156-47-4

Basic information

• Product Name: 4-(3,5-dimethylphenyl)butanoic acid
• Synonyms: 4-(3,5-dimethylphenyl)butanoic acid
• CAS NO: 22156-47-4
• Molecular Weight: 192.258
• Mol File: 22156-47-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-(3,5-dimethylphenyl)butanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3,5-dimethylphenyl)butanoic acid(22156-47-4)
• EPA Substance Registry System: 4-(3,5-dimethylphenyl)butanoic acid(22156-47-4)

Safety Data

• Hazardous Substances Data: 22156-47-4(Hazardous Substances Data)

Upstream product

• 556-96-7 5-bromo-1,3-xylene 
• 77446-17-4 1-allyl-3,5-dimethylbenzene 
• 5779-95-3 3,5-dimethylbenzaldehyde 
• 36440-57-0 methyl 4-(3,5-dimethylphenyl)-4-oxobutanoate 
• 313058-69-4 2-[3-(3,5-dimethyl-phenyl)-propyl]-[1,3]dioxolane 
• 36440-58-1 4-(3,5-dimethylphenyl)-4-oxobutanoic acid 

Downstream Products

• 17057-91-9 2,4,5-trimethylnaphthalene 
• 13621-25-5 5,7-dimethyltetralone 

Relevant articles and documents

Carbonylative Transformation of Allylarenes with CO Surrogates: Tunable Synthesis of 4-Arylbutanoic Acids, 2-Arylbutanoic Acids, and 4-Arylbutanals

In this Communication, procedures for the selective synthesis of 4-arylbutanoic acids, 2-arylbutanoic acids, and 4-arylbutanals from the same allylbenzenes have been developed. With formic acid or TFBen as the CO surrogate, reactions proceed selectively and effectively under carbon monoxide gas-free conditions.

Integrated chemical process: One-pot aromatization of cyclic enones by the double elimination methodology

A variety of aromatic hydrocarbons bearing multiple alkyl substituents are accessible with perfect regiocontrol in a one-pot reaction starting from cyclo-hexenones and their aromatic analogues [Eq. (1)]. The present methodology can be further extended to the synthesis of polycyclic aromatic hydrocarbons. The drawbacks encountered in the Friedel-Crafts reaction are resolved since the reaction proceeds under basic conditions.