221637-45-2Relevant academic research and scientific papers
6-thioguanine in peptide nucleic acids. Synthesis and hybridization properties
Hansen, Henrik F.,Christensen, Leif,Dahl, Otto,Nielsen, Peter E.
, p. 5 - 9 (2007/10/03)
The synthesis of N-((2-amino-6-benzylthiopurine-9-yl)acetyl)-N-(2- tBocaminoethyl)glycine 4 and its incorporation into a peptide nucleic acid (PNA) oligomer are described. Introduction of a single 6-thioguanine residue (6sG) in the PNA of a 10-mer PNA:DNA
