221638-18-2

Upstream product

• 108-24-7 acetic anhydride 
• 221638-17-1 (4R,5R)-2,2-Dimethyl-4-phenyl-5-((S)-toluene-4-sulfinylmethyl)-[1,3]dioxolane 
• 221638-16-0 (1R,2R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-phenyl-3-((S)-toluene-4-sulfinyl)-propan-1-ol 
• 221638-15-9 (R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-phenyl-3-((S)-toluene-4-sulfinyl)-propan-1-one 
• 221638-14-8 2-hydroxy-N-methoxy-N-methyl-3-(toluene-4-sulfinyl)-propionamide 

Relevant academic research and scientific papers

Stereoselective sulfoxide directed reduction of 1,2-diketo-derivatives to enantiomerically pure syn and anti 1,2-diols. Correction of the relative configuration by X-ray and chemical correlation to goniobutenolides A and B

In our recent report on the enantioselective synthesis of syn and anti 1,2-diols from oxalyl-di-(N-methyl-N-methoxyamide), an unfortunate sample inversion for 13C NMR analysis led us to an incorrect attribution of their relative configurations. We report now the correction of the configurations of these diols by X-ray analysis and chemical correlation to two known natural products, goniobutenolides A and B.