221646-18-0

Upstream product

• 83-40-9 3-methylsalicylic acid 
• 36805-97-7 N,N-dimethylformamide di-tert-butyl acetal 
• 71432-55-8 2-tert-butyl-1,3-diisopropylisourea 

Downstream Products

• 221646-19-1 2-acetoxy-3-methyl-benzoic acid tert-butyl ester 
• 221646-21-5 2-(2-acetoxy-3-tert-butoxycarbonyl-benzyl)-2-phenylacetylamino-malonic acid diethyl ester 
• 221646-22-6 2-(3-carboxy-2-hydroxy-benzyl)-2-phenylacetylamino-malonic acid 
• 221646-23-7 (rac)-N-phenylacetyl-3-carboxy-2-hydroxyphenylalanine 
• 221646-17-9 8-carboxy-3-phenylacetamido-3,4-dihydro-2H-1-benzopyran-2-one 
• 221646-20-4 2-acetoxy-3-bromomethyl-benzoic acid tert-butyl ester 

Relevant academic research and scientific papers

Microwave-assisted ester formation using O-alkylisoureas: A convenient method for the synthesis of esters with inversion of configuration

(Chemical Equation Presented) The formation of carboxylic esters via reaction of carboxylic acids with O-alkylisoureas proceeds in excellent yields with very short reaction times when conducted in a monomode microwave synthesizer. Efficient processes were

A 'cephalosporin-like' cyclic depsipeptide: Synthesis and reaction with β-lactam-recognizing enzymes

The cyclic depsipeptide 8-carboxy-3-phenylacetamido-3,4-dihydro-2H-1- benzopyran-2-one, a cyclic analog of aryl phenaceturates with structural similarity to cephalosporins, has been synthesized as a potential substrate/inhibitor of β-lactam-recognizing enzymes. It was found to be a tight-binding, poor substrate of class A β-lactamases and an irreversible inhibitor of several DD-peptidases.