221655-54-5Relevant academic research and scientific papers
Preparation method of sofosbuvir impurity
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Paragraph 0021; 0048; 0050-0052; 0054-0055; 0057-0058; 0060, (2021/04/21)
The invention discloses a preparation method of a sofosbuvir impurity, the sofosbuvir impurity is an impurity SM1-Q7, and the sofosbuvir impurity is prepared by one of the following two synthesis routes. The method has the advantages of easily available raw materials, mild reaction conditions and simple operation, and the obtained SM1-Q7 has good purity and meets the requirements of research and control of sofosbuvir impurities.
