221678-47-3

Basic information

• Product Name: (3S,4R)-1-allyloxalyl-4-[(2S,6R)-2-[(S)-(1-allyloxycarbonyl)pyrrolidin-3-ylmethylthio]cyclohexanon-6-yl]-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl]azetidin-2-one
• CAS NO: 221678-47-3
• Molecular Weight: 636.882
• Mol File: 221678-47-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3S,4R)-1-allyloxalyl-4-[(2S,6R)-2-[(S)-(1-allyloxycarbonyl)pyrrolidin-3-ylmethylthio]cyclohexanon-6-yl]-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl]azetidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3S,4R)-1-allyloxalyl-4-[(2S,6R)-2-[(S)-(1-allyloxycarbonyl)pyrrolidin-3-ylmethylthio]cyclohexanon-6-yl]-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl]azetidin-2-one(221678-47-3)
• EPA Substance Registry System: (3S,4R)-1-allyloxalyl-4-[(2S,6R)-2-[(S)-(1-allyloxycarbonyl)pyrrolidin-3-ylmethylthio]cyclohexanon-6-yl]-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl]azetidin-2-one(221678-47-3)

Safety Data

• Hazardous Substances Data: 221678-47-3(Hazardous Substances Data)

Upstream product

• 221678-45-1 (3S,4R)-4-[(1S,2S,6R)-2-[(S)-(1-allyloxycarbonyl)pyrrolidin-3-ylmethylthio]-1-hydroxycyclohexan-6-yl]-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl]azetidin-2-one 
• 135297-04-0 (3S,4R)-4-[(1R,2S,3R)-2,3-epoxycyclohexyl]-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl]azetidin-2-one 
• 74503-07-4 allyl oxalyl chloride 
• 221678-46-2 (3S,4R)-4-[(2S,6R)-2-[(S)-(1-allyloxycarbonyl)pyrrolidin-3-ylmethylthio]cyclohexanon-6-yl]-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl]azetidin-2-one 

Relevant articles and documents

Synthesis and biological evaluation of novel tricyclic carbapenems (Trinems)

Synthesis of new tricyclic carbapenems (trinems) with a pyrrolidinyl moiety at the C-4 position of the tricyclic ring and their antimicrobial activities were studied. These trinems showed potent activities against Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA). Among them, (4R)-[(S)-pyrrolidin-3-ylthiomethyl]trinem (14a) exhibited good activity against MRSA in vitro and in vivo.