22174-47-6Relevant academic research and scientific papers
POLAR EFFECT OF SUBSTITUENTS IN THE REACTION OF OXIDES OF SUBSTITUTED BENZYLIDENEACETOPHENONES WITH MORPHOLINE IN ACETONITRILE
Semenova, S. N.,El Sadani, S. K.,Karavan, V. S.,Temnikova T. I.
, p. 864 - 867 (2007/10/02)
The action of morpholine on the oxides of substituted trans-benzylideneacetophenones in acetonitrile leads to opening of the oxide ring on the side of the β-carbon atom.The dependence of the rate constants on the polar effect of the substituents at the central carbon atom has V-shaped character and not linear as in methanol .The results are explained by an increase on the "compactness" of the transition state in the less electrophilic solvent acetonitrile.
