22186-60-3

Usage

Uses

Used in Pharmaceutical Industry:
2-(1H-pyrrol-2-yl)ethanol is used as a building block in the synthesis of pharmaceuticals for its versatile chemical properties and potential to contribute to the development of new drugs.
Used in Agrochemical Industry:
2-(1H-pyrrol-2-yl)ethanol is used as a component in agrochemicals for its potential to be incorporated into formulations that exhibit antibacterial and antifungal properties, contributing to crop protection and disease management.
Used in Antimicrobial Formulations:
2-(1H-pyrrol-2-yl)ethanol is used as an active ingredient in antimicrobial formulations due to its demonstrated antibacterial and antifungal properties, making it a potential candidate for use in various applications where microbial control is necessary.
Used as a Chelating Agent:
2-(1H-pyrrol-2-yl)ethanol is used as a chelating agent for metal ions, which can be beneficial in various industrial processes where metal ion management is required, such as in water treatment or chemical synthesis.
Used in Organic Synthesis:
2-(1H-pyrrol-2-yl)ethanol is used as a building block in organic synthesis, allowing for the creation of a wide range of organic compounds for various applications across different industries.

InChI:InChI=1/C6H9NO/c8-5-3-6-2-1-4-7-6/h1-2,4,7-8H,3,5H2

Upstream product

• 4778-25-0 (1H-pyrrol-2-yl)acetic acid ethyl ester 
• 75-21-8 oxirane 
• 109-97-7 pyrrole 
• 96999-22-3 n-octyl pyrrole-2-glyoxalate 
• 3768-70-5 Pyrryl-2-glyoxylylchlorid 
• 53912-79-1 pyrrol-2-yl-acetic acid methyl ester 

Downstream Products

• 19432-88-3 2-(β-hydroxyethyl)-pyrrolidine 
• 175689-46-0 2-(2-pyrrolyl)ethyl 4-phenyl-3(E)-butenoate 
• 175689-47-1 <1-(1,1-dimethylethoxycarbonyl)-2-pyrrolyl>ethyl 2-diazo-4-phenyl-3(E)-butenoate 
• 1551-06-0 2-ethyl-1H-pyrrole 
• 84573-35-3 perhydropyrrolo<1,2-c><1,3>oxazine 

Relevant academic research and scientific papers

Novel quinazoline derivative LU1508, and preparation method and application thereof

The invention discloses a novel quinazoline derivative LU1508, and a preparation method thereof. The chemical name of the derivative is 4[{4-[(7-methoxy)-6-(1-pyrrolyl-2-yl)hydroxyethyl]quinazolinyl-4-yl}aminophenylaminomethylphenol. The quinazoline deriv

Novel quinazoline derivative LU1502 as well as preparation method and application thereof

The invention discloses a novel quinazoline derivative LU1502 as well as a preparation method thereof. The quinazoline derivative LU1502 is chemically named N-[(4-fluorophenyl)methyl]-4-N-[7-methoxy-6-[2-(1-pyrrole-2-yl)hydroxyethyl]quinazoline-4-yl]-1,4-diamine. The quinazoline derivative as well as pharmaceutically acceptable salts, solvates and hydrates thereof has excellent in-vitro and in-vivo anti-tumor activity for MDA-MB-435, SK-BR-3, A549, HCT 115 and MDA-MB-468 and has brighter application prospect in preparation of anti-tumor drugs.

Novel quinazoline derivative LU1506, preparation method and applications thereof

The invention discloses a novel quinazoline derivative LU1506 and a preparation method thereof. The derivative is chemically named as N-{[(4-dimethylamino)phenyl]methyl}-4-N-[7-methoxyl-6-(2-pyrrolidyl)hydroxyethyl]quinazoline-4-yl}benzene-1,4-diamine. The provided quinazoline derivative, pharmaceutically acceptable salts, solvates, and hydrates thereof have an excellent in-vitro/in-vivo antitumor activity on MCF-7, SK-BR-3, MDA-MB-468, U-118 MG, HTC116, and U-87 MG, and can be used to prepare antitumor drugs.

Novel quinazoline derivative LU1510 as well as preparation method and application thereof

The invention discloses a novel quinazoline derivative LU1510 as well as a preparation method thereof. The quinazoline derivative LU1510 is chemically named N-4-[(4-dimethylamino phenyl)methoxy]phenyl-7-methoxy-6-[(1-pyrrole-2-yl)hydroxyethyl]quinazoline-

Novel quinazoline derivative LU1504 and preparing method and application thereof

The invention discloses a novel quinazoline derivative LU1504 and a preparing method thereof. The chemical name of the derivative is N-{7-methoxy-6-[2-(1-pyrrole-2-base) ethoxy] quinazoline-4 base}-4-N-[(4-nitrobenzophenone) methyl] benzene-1,4-diamine. The quinazoline derivative and pharmaceutically acceptable salt, solvate and aquo-complex thereof have excellent anti-tumor in vitro and in vivo activity on MCF-7, A549 and HT-29 and have broad application prospects in preparing anti-tumor drugs.

Synthesis of Alkylpyrroles by the Sodium Borohydride Reduction of Acylpyrroles

N-Unsubstituted alkylpyrroles are obtained by the reduction of the corresponding acylpyrroles with sodium borohydride in boiling 2-propanol.This reaction was demonstrated to proceed via the pyrrolylalkylcarbinol and was extended to the synthesis of a branched chain alkylpyrrole 25 from the tertiary alcohol 24.

Compounds with Bridgehead Nitrogen. 42 - 1H NMR and Stereochemistry of Isomeric 6a-Methylperhydroindolobenzoxazines and the Position of Conformational Equilibrium in Perhydropyrrolooxazine

The 1H NMR parameters of the NCH2O protons in the spectrum of perhydropyrrolooxazine show its existence in solution at room temperature in the O-inside cis-fused conformation, rel-(3aS,6aS,6bR,10aS,11aS)6a-Methylperhydroindolobenzoxazine and rel-(3aS,6aS,6bS,10aR,11aS)-6a-methylperhydroindolobenzoxazine are shohn to adopt cis- and trans-fused conformations, respectively, for the corresponding bicyclic moiety.