221906-99-6

Upstream product

• 1120-64-5 2-methyl-4,5-dihydro-1,3-oxazole 
• 100-47-0 benzonitrile 

Downstream Products

• 74405-84-8 7-phenyl-2,3-dihydro-5H-[1,3]oxazolo[3,2-a]pyrimidin-5-one 
• 1144524-80-0 7-phenyl-2,3-dihydro-5H-[1,3]oxazolo[3,2-c]pyrimidin-5-one 
• 1144524-83-3 3-(2-chloroethyl)-6-phenyl-1,2,3,4-tetrahydro-2,4-pyrimidindione 
• 3646-50-2 3-Amino-3-phenylpropionic acid 
• 334817-23-1 2-(2-amino-2-phenyl)ethyl-2-oxazoline 
• 221907-26-2 (Z)-2-(4,5-dihydro-1,3-oxazol-2-yl)-1-phenyl-1-propen-1-amine 

Relevant academic research and scientific papers

An efficient synthesis of uracil derivatives from 2-alkyl-Δ2-oxazolines and nitriles

An efficient and convenient synthesis of new fluorinated and non-fluorinated uracils is described herein. The condensation of nitriles with enolates generated from 2-alkyl-Δ2-oxazolines (I) affords fluorinated β-enamino acid derivatives, which

Synthesis and C-alkylation of C-protected β-enamino acid derivatives from oxa- thia- and imidazolines

Various heterocycles 3a-h can be readily metallated and condensed with a variety of organic nitriles to afford C-protected β-enamino acid derivatives 1 (or 2). Procedures for alkylation of compounds 1 to obtain 2 as well as a 'one-pot' preparation of 2 from 3 are also described.