22192-08-1

Basic information

• Product Name: 2,6-dimethyl-1-phenylpyridin-4(1H)-one
• CAS NO: 22192-08-1
• Molecular Formula: C₁₃H₁₃NO
• Molecular Weight: 199.2484
• Mol File: 22192-08-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 300.6°C at 760 mmHg
• Flash Point: 108.4°C
• Density: 1.102g/cm³
• Vapor Pressure: 0.00111mmHg at 25°C
• Refractive Index: 1.575
• CAS DataBase Reference: 2,6-dimethyl-1-phenylpyridin-4(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-dimethyl-1-phenylpyridin-4(1H)-one(22192-08-1)
• EPA Substance Registry System: 2,6-dimethyl-1-phenylpyridin-4(1H)-one(22192-08-1)

Safety Data

• Hazardous Substances Data: 22192-08-1(Hazardous Substances Data)

Upstream product

• 34793-66-3 hepta-2,5-diyn-4-one 
• 62-53-3 aniline 
• 626-53-9 1,3-diacetyl acetone 
• 3512-75-2 4-chloro-2,6-lutidine 
• 71-43-2 benzene 
• 697-92-7 2,6-dimethyl-4-chloropyridine N-oxide 
• 50428-54-1 hepta-2,5-diyn-4-ol 
• 108-22-5 Isopropenyl acetate 
• 26567-78-2 (Z)-4-(phenylamino)-3-penten-2-one 
• 520-45-6 Dehydracetic acid 
• 56-23-5 tetrachloromethane 

Downstream Products

• 105911-88-4 2,6-dimethyl-1-phenyl-1H-pyridin-4-one-hydrazone; dihydrochloride 
• 109649-35-6 (2,6-dimethyl-1-phenyl-1H-[4]pyridylidene)-(4-nitro-benzylidene)-hydrazine 
• 112324-55-7 (2,6-dimethyl-1-phenyl-1H-[4]pyridyliden)-(4-oxo-4H-[1]naphthylidene)-hydrazine 
• 102238-35-7 benzoic acid-(2,6-dimethyl-1-phenyl-1H-[4]pyridylidenehydrazide) 
• 111691-44-2 (2,6-dimethyl-1-phenyl-1H-[4]pyridyliden)-(4-oxo-cyclohexa-2,5-dienylidene)-hydrazine 
• 13895-45-9 4-(2,6-dimethyl-1-phenyl-1H-pyridin-4-ylidene)-2-phenyl-4H-oxazol-5-one 
• 108872-31-7 4-chloro-2,6-dimethyl-1-phenyl-pyridinium; chloride 
• 110532-55-3 4-chloro-2,6-dimethyl-1-phenyl-pyridinium; benzenesulfonate 

Relevant articles and documents

C-H Pyridonation of (Hetero-)Arenes by Pyridinium Radical Cations

Pyridones are important heteroaromatic scaffolds found in natural products and pharmaceuticals and are, therefore, of major interest in organic synthetic chemistry. Here we report the first C-H pyridonation of unactivated (hetero-)arenes, providing a methodology to directly access N-aryl-2- and 4-pyridones. Generation of pyridinium radical cations through single-electron reduction allows for the synthesis of pyridones on structurally complex molecules.