22195-38-6

Basic information

• Product Name: 4-(chloromethyl)-2,2-diphenyl-1,3-dioxolane
• Synonyms: 4-(chloromethyl)-2,2-diphenyl-1,3-dioxolane
• CAS NO: 22195-38-6
• Molecular Formula: C₁₆H₁₅ClO₂
• Molecular Weight: 274.7421
• Mol File: 22195-38-6.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(chloromethyl)-2,2-diphenyl-1,3-dioxolane(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(chloromethyl)-2,2-diphenyl-1,3-dioxolane(22195-38-6)
• EPA Substance Registry System: 4-(chloromethyl)-2,2-diphenyl-1,3-dioxolane(22195-38-6)

Safety Data

• Hazardous Substances Data: 22195-38-6(Hazardous Substances Data)

Upstream product

• 119-61-9 benzophenone 
• 106-89-8 epichlorohydrin 
• 96-24-2 3-monochloro-1,2-propanediol 

Downstream Products

• 1220748-12-8 C₂₅H₂₇NO₄ 
• 1220748-13-9 C₂₆H₂₉NO₅ 
• 1220748-18-4 C₃₀H₂₉NO₃ 
• 1220748-10-6 C₂₆H₂₉NO₃ 
• 1220748-14-0 C₂₆H₂₉NO₅ 
• 1220748-15-1 C₂₆H₂₉NO₅ 
• 1220748-16-2 C₂₆H₂₉NO₄ 
• 1220748-11-7 C₂₅H₂₇NO₄ 
• 1220748-20-8 C₃₀H₂₉NO₃ 
• 1220748-19-5 C₃₀H₂₉NO₃ 
• 124918-09-8 (4S)-2,2-diphenyl-4-(hydroxymethyl)-1,3-dioxolane 
• 522616-93-9 (2,2-diphenyl[1,3]dioxolan-4-ylmethyl)(2-phenoxyethyl)carbamic acid ethyl ester 
• 522616-94-0 (2,2-diphenyl[1,3]dioxolan-4-ylmethyl)methyl(2-phenoxyethyl)amine 
• 522616-89-3 [(2,2-diphenyl-1,3-dioxolan-4-yl)methyl]-2-phenoxyethylamine 

Relevant articles and documents

Scouting new sigma receptor ligands: Synthesis, pharmacological evaluation and molecular modeling of 1,3-dioxolane-based structures and derivatives

Herein we report the synthesis and biological activity of new sigma receptor (σR) ligands obtained by combining different substituted five-membered heterocyclic rings with appropriate σR pharmacophoric amines. Radioligand binding assay, performed on guine

Enzymatic resolution of 2,2-disubstituted-1,3-dioxolane-4-methanol carboxylic esters

The enantioselectivity of enzymatic hydrolysis of carboxylic esters of various 1,2-ketals of glycerol has been investigated. The influence of the ketal group has been studied. A number of lipases and proteinases have been tested and the best enantioselectivity was obtained with proteinase from Aspergillus oryzae which gave an E-value of 9 with 2,2-dimethyl-1,3-dioxolane-4-methanol butanoate. Variations in the acyl part revealed that butanoyl was optimal. All hydrolysis products have been synthesised in homochiral forms from homochiral starting materials.