222016-62-8Relevant academic research and scientific papers
α-Chloroalkylmagnesium reagents of >90% ee by sulfoxide/magnesium exchange
Hoffmann, Reinhard W.,Nell, Peter G.
, p. 338 - 340 (2007/10/03)
Not only for ligand exchange at sulfoxides can the sulfoxide/magnesium exchange reaction be used, but it also provides a possibility to generate Grignard reagents in way that avoids metallic magnesium and thus radical processes. Therefore, enantiomerically pure Grignard reagents can be obtained from the corresponding sulfoxides [Eq. (a)].
