222016-68-4Relevant articles and documents
Highly enantiomerically enriched α-haloalkyl grignard reagents
Hoffmann, Reinhard W.,Nell, Peter G.,Leo, Roland,Harms, Klaus
, p. 3359 - 3365 (2007/10/03)
α-Chloro- and α-bromoalkyl Grignard reagents 11 and 30 with > 97% ee (enantiomeric excess) were generated by a sulfoxide/magnesium exchange reaction from the enantiomerically and diastereomerically pure sulfoxides 25 and 27. The resulting α-haloalkyl Grig