222046-90-4

Usage

Uses

Used in Pharmaceutical Industry:
2-Thiophenecarboxylic acid, tetrahydro-5-oxo(9CI) is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its presence in the thiophene carboxylic acid class suggests that it may be involved in the development of new drugs or the modification of existing ones, given the electronic properties of thiophene compounds.
Used in Organic Materials:
2-Thiophenecarboxylic acid, tetrahydro-5-oxo(9CI) is used as a component in the development of organic materials. The electronic properties of thiophene compounds make them valuable in the creation of materials with specific characteristics, such as conductivity or stability, which can be utilized in various industries.
Further research may be needed to fully understand the characteristics and potential applications of 2-Thiophenecarboxylic acid, tetrahydro-5-oxo(9CI), as it is a less common and under-studied compound.

Upstream product

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Relevant academic research and scientific papers

COMPOSITION COMPRISING BISTHIOLACTONES AND PROCESS FOR TREATING KERATIN MATERIALS USING SAME

The present invention relates to i) a process for treating keratin materials, in particular human keratin fibres, comprising the application of a composition comprising at least one bisthiolactone of formula (I), in particular for shaping keratin fibres and/or straightening/relaxing, ii) a composition comprising the bisthiolactone(s) of formula (I), iii) novel bisthiolactones of formula (I), iv) a process for preparing the novel bisthiolactones of formula (I), and v) the use of said bisthiolactones in cosmetics. In which formula (I), R1, R2, R3, R4, X, X', Y, Y', A, A', B, a, b, c, and d are as defined in the description.

Preparation of carboxythiolactones and their active derivatives

The design of peptidyl immunogens requires that a number of elements be covalently linked to enable the appropriate immune response to occur. Two of these elements are: (a) T-cell sequences which after processing, bind to major histocompatibility complex (MHC) molecules and T-cell receptors and (b) B-cell sequences which embody the constellation of atoms which will ultimately be recognized by the desired antibody. Our concept, designed to effectuate this, involved a single molecule which could conjugate three peptides, potentially in discrete steps, in one pot. Activated carboxythiolactones, hitherto unknown entities, provide such a system: two acyl sites susceptible to nucleophilic attack at disparate rates and a liberated thiol susceptible to electrophilic alkylation. Such a set of thiolactones and their derivatives have been synthesized from inexpensive starting materials and their reactivities are under investigation. If successful, the system will not only obviate the difficult syntheses of longer linear peptides, but will also allow a rapid structural permutation of the various elements.