22205-64-7

Basic information

• Product Name: Thiocyanic acid piperidine
• Synonyms: thiocyanic acid, compound with piperidine (1:1);PiperidineThiocyanate;Thiocyanic acid piperidine;Thiocyanic acid piperidine (1:1)
• CAS NO: 22205-64-7
• Molecular Formula: CNS*C₅H₁₂N
• Molecular Weight: 144.24
• EINECS: 244-843-4
• Mol File: 22205-64-7.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 106.4°Cat760mmHg
• Flash Point: 4.4°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 28.3mmHg at 25°C
• CAS DataBase Reference: Thiocyanic acid piperidine(CAS DataBase Reference)
• NIST Chemistry Reference: Thiocyanic acid piperidine(22205-64-7)
• EPA Substance Registry System: Thiocyanic acid piperidine(22205-64-7)

Safety Data

• Hazardous Substances Data: 22205-64-7(Hazardous Substances Data)

Usage

General Description

Thiocyanic acid piperidine is a chemical compound that consists of a piperidine molecule with a thiocyanic acid group attached to it. The thiocyanic acid group contains a sulfur atom bonded to a carbon atom, which is further bonded to a nitrogen atom. The piperidine molecule is a heterocyclic organic compound containing a six-membered ring with five carbon atoms and one nitrogen atom. Thiocyanic acid piperidine is commonly used in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It is also known for its use as a reagent in chemical reactions to introduce thiol groups into organic molecules. Additionally, it has been studied for its potential biological activities, including antimicrobial and anticancer properties.

InChI:InChI=1/C5H11N.CHNS/c1-2-4-6-5-3-1;2-1-3/h6H,1-5H2;3H

Upstream product

• 110-89-4 piperidine 
• 155816-23-2 disulfur dithiocyanate 
• 56-23-5 tetrachloromethane 
• 57670-85-6 sulfur dirhodanide 
• 1147550-11-5 ammonium thiocyanate 
• 112404-82-7 4-pentinoyl isothiocyanate 
• 18991-39-4 p-methylbenzyl thiocyanate 
• 1986-38-5 2-thioxo-[1,3]thiazinan-4-one 

Relevant articles and documents

Thermal studies on piperidinium hexathiocyanatochromate(III)

Piperidinium hexathiocyanatochromate(III), (pipH)3[Cr(NCS)6], was synthesized using the molten salt pipHSCN and was found to contain nitrogen-bonded thiocyanate. The (pipH)3[Cr(NCS)6] decomposes in the range 250

Nucleophilic Substitution on 4-Methylbenzyl Thiocyanate with Nucleophiles

The reactions of 4-methylbenzyl thiocyanate (1) with several nucleophiles have been investigated.Compound 1 possesses three electrophilic sites, i.e., benzylic carbon, sulfur and cyano carbon, to receive nucleophilic attack.PhS- and CN- which have HOMO's of high energy levels appear to attack preferentially the sulfur atom.MeO- was found to attack preferably the cyanide carbon, while amines which have HOMO's of low energy levels prefer benzylic carbon to attack.The nucleophilic substitution on the sulfur or the cyanide carbon generates CN- or p-xylene-α-thiolate anion, strong nucleophiles, as the primary products, which then initiate the complex secondary reactions.The selective reactivities of three attacking sites for nucleophiles in 1 have been rationalized in terms of MO theory.

1,3-thiazines, XIII: Reactions of 4-oxo-2-thioxo- and 2,4-dioxo-tetrahydro-1,3-thiazines with some nucleophiles, II

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