2221-66-1

Basic information

• Product Name: 2H,8H-Benzo[1,2-b:3,4-b']dipyran-2-one,9,10-dihydro-8,8-dimethyl- (8CI,9CI)
• Synonyms: 6-Chromanacrylicacid, 5-hydroxy-2,2-dimethyl-, d-lactone (6CI,7CI); Dihydroseselin; Seselin, dihydro-
• CAS NO: 2221-66-1
• Molecular Formula: C14H14 O3
• Mol File: 2221-66-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2H,8H-Benzo[1,2-b:3,4-b']dipyran-2-one,9,10-dihydro-8,8-dimethyl- (8CI,9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2H,8H-Benzo[1,2-b:3,4-b']dipyran-2-one,9,10-dihydro-8,8-dimethyl- (8CI,9CI)(2221-66-1)
• EPA Substance Registry System: 2H,8H-Benzo[1,2-b:3,4-b']dipyran-2-one,9,10-dihydro-8,8-dimethyl- (8CI,9CI)(2221-66-1)

Safety Data

• Hazardous Substances Data: 2221-66-1(Hazardous Substances Data)

Usage

General Description

2H,8H-Benzo[1,2-b:3,4-b']dipyran-2-one,9,10-dihydro-8,8-dimethyl- (8CI,9CI) is a chemical compound with a molecular formula C20H16O2. It belongs to the class of organic compounds known as chromones, which are characterized by their 4H-pyranone core structure. This particular compound is a derivative of chromone and is classified as a flavonoid. Its structure contains two fused benzene rings and a pyranone ring, as well as two methyl groups attached to the pyranone ring. The compound has potential biological activities and may be of interest for further research in the fields of pharmacology and medicine.

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Relevant articles and documents

A new synthetic route to dihydrobenzopyran via tandem demethylation cyclisation

A tandem demethylation-cyclisation reaction resulting in the formation of pyran rings using AlCl3/EtSH reagent under mild reaction conditions is reported. X-ray diffraction studies on the intermediate support the suggested mechanism.

Novel synthesis of dihydroxanthyletin and dihydroseselin derivatives

In a one-step alkylation, ring-closure 7-hydroxycoumarins are condensed in acid media with allyl and homoallyl halides or alcohols to linear 6,7-dihydro-2H,8H-benzo[1,2-b:5,4-b']dipyran-2-ones. If both carbon-6 and carbon-8 are unsubstituted in the original coumarin, cyclization to angular isomers 9,10-dihydro-2H,8H-benzo[1,2-b:3,4-b']dipyran-2- ones competes. These compounds are higher ring homologs of psoralens and angelicins commonly employed in phototherapy of skin disorders.