222168-69-6Relevant articles and documents
General synthetic method for naphthyridines and their N-oxides containing isoquinolinic nitrogen
Numata, Atsushi,Kondo, Yoshinori,Sakamoto, Takao
, p. 306 - 311 (2007/10/03)
Substituted naphthyridines containing isoquinolinic nitrogen were synthesized by the reaction of o-ethynylpyridinecarbaldehydes with ammonia. The synthesis of their N-oxides was also achieved by a basic cyclization reaction of the same pyridine derivatives via the corresponding oximes.