222168-79-8

Upstream product

• 70201-43-3 3-bromo-pyridine-4-carbaldehyde 
• 626-55-1 3-Bromopyridine 
• 222167-48-8 3-(2-phenylethynyl)pyridine-4-carboxaldehyde 

Downstream Products

• 1589566-29-9 (Z)-1-(1-(3-benzylidene-1,3-dihydroisobenzofuran-1-yl)cyclopropyl)-3-phenyl-2,6-naphthyridine 

Relevant academic research and scientific papers

General synthetic method for naphthyridines and their N-oxides containing isoquinolinic nitrogen

Substituted naphthyridines containing isoquinolinic nitrogen were synthesized by the reaction of o-ethynylpyridinecarbaldehydes with ammonia. The synthesis of their N-oxides was also achieved by a basic cyclization reaction of the same pyridine derivatives via the corresponding oximes.