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α-Amino-α-phenyl-malonsaeure-diaethylester, also known as α-amino-α-phenylmalonic acid diethyl ester, is an organic compound with the chemical formula C13H15NO4. It is a white crystalline solid that is soluble in organic solvents. α-Amino-α-phenyl-malonsaeure-diaethylester is a derivative of α-amino-α-phenylmalonic acid, where the carboxylic acid groups are esterified with ethanol. It is used as an intermediate in the synthesis of various pharmaceuticals and chemical compounds, particularly in the production of certain antibiotics and other biologically active molecules. The compound is also of interest in organic chemistry research due to its potential applications in the formation of complex molecules and its role in studying peptide synthesis.

22225-53-2

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22225-53-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 22225-53-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,2,2 and 5 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 22225-53:
(7*2)+(6*2)+(5*2)+(4*2)+(3*5)+(2*5)+(1*3)=72
72 % 10 = 2
So 22225-53-2 is a valid CAS Registry Number.

22225-53-2Downstream Products

22225-53-2Relevant academic research and scientific papers

Improved Reagent for Electrophilic Amination of Stabilized Carbanions

Smulik, Jason A.,Vedejs, Edwin

, p. 4187 - 4190 (2007/10/03)

(Equation presented) Enolate amination using O-di(p-methoxyphenyl) phosphinylhydroxylamine 2 is reported. Reagent 2 reacts efficiently with stabilized sodium or potassium enolates derived from malonates, phenylacetates, and phenylacetonitriles and is sufficiently soluble for use in solution at -78°C.

PRIMARY AMINES VIA ELECTROPHILIC AMINATION OF ORGANOMETALLIC COMPOUNDS WITH O-(DIPHENYLPHOSPHINYL)HIDROXYLAMINE

Boche, Gernot,Bernheim, Michael,Schrott, Wolfgang

, p. 5399 - 5402 (2007/10/02)

It is shown that O-(diphenylphosphinyl)hydroxylamine 4a transforms all kinds of "carbanions" into primary amines; best yields are received with "stabilized anions", e.g. of the benzylic type.

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