22230-37-1

Upstream product

• 619-45-4 4-methoxycarbonyl aniline 
• 25271-63-0 4-((4-(methoxycarbonyl)phenyl)amino)butane-1-sulfonic acid 
• 22351-81-1 4-(4-chloro-butane-1-sulfonylamino)-benzoic acid 

Downstream Products

• 1609355-26-1 C₂₅H₂₁ClN₄O₃S 
• 1609355-27-2 C₂₅H₂₁ClN₄O₃S 
• 1609355-28-3 C₂₅H₂₁ClN₄O₃S 
• 22230-38-2 4-(1,1-dioxo-1λ⁶-[1,2]thiazinan-2-yl)-benzoyl chloride 

Relevant academic research and scientific papers

CYCLIC SULFONAMIDE CONTAINING DERIVATIVES AS INHIBITORS OF HEDGEHOG SIGNALING PATHWAY

The invention relates generally to the creation and use of cyclic sulfonamide containing derivatives to inhibit the hedgehog signaling pathway and to the use of those compounds for the treatment of hyperproliferative diseases and angiogenesis mediated diseases.

Benzamide nitriles

Compounds of the formula (I) wherein m, n, A, R1, R2, R3, R4, R5 and R6 are as described herein, together with methods for making the compounds and using the compounds for treatment of diseases or conditions mediated by Cathepsin K.