222307-20-2

Upstream product

• 34837-55-3 Phenylselenyl bromide 
• 222307-14-4 (S)-(+)-N-tert-butyloxycarbonyl-5-(triisopropylsilyloxymethyl)-pyrrolidin-2-one 
• 222307-13-3 (S)-(+)-5-(triisopropylsilyloxymethyl)-pyrrolidin-2-one 
• 17342-08-4 (S)-Pyroglutaminol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 13154-24-0 triisopropylsilyl chloride 

Relevant academic research and scientific papers

Photoinduced addition of methanol to 5(S)-5-triisopropylsiloxymethyl-N- boc-dihydropyrrole-2(5H)-one: A new route to 4(S), 5(S)-disubstituted pyrrolidin-2-ones

We describe the photoinduced addition of methanol to 5(S)-5- triisopropylsiloxymethyl-N-boc-dihydropyrrole-2(5H)-one to produce 5(S)-5- triisopropylsiloxymethyl-4(S)-hydroxymethyl-pyrrolidine-2-one, and conversion of this into a variety of 4(S), 5(S)-pyrrolidine-2-ones. Photo-induced addition of methanol to 5(R)-N-boc-5-amino-dihydropyran-2(5H)-one yielded the unexpected product 4(S)-1'-[2'-hydroxy, 1'-(R)-N-boc-amino]ethyl- tetrahydrofuran-2-one via rearrangement of the initial photoadduct.