222400-05-7

Basic information

• Product Name: Carbamic acid, N-(4-nitrosophenyl)-, methyl ester
• Synonyms: Carbamic acid, N-(4-nitrosophenyl)-, methyl ester
• CAS NO: 222400-05-7
• Molecular Formula: C₈H₈N₂O₃
• Molecular Weight: 0
• Mol File: 222400-05-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Carbamic acid, N-(4-nitrosophenyl)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, N-(4-nitrosophenyl)-, methyl ester(222400-05-7)
• EPA Substance Registry System: Carbamic acid, N-(4-nitrosophenyl)-, methyl ester(222400-05-7)

Safety Data

• Hazardous Substances Data: 222400-05-7(Hazardous Substances Data)

Upstream product

• 2603-10-3 N-phenyl methyl carbamate 

Downstream Products

• 92166-43-3 (4-phenylazo-phenyl)-carbamic acid methyl ester 
• 1943-87-9 methyl N-(4-nitrophenyl)carbamate 
• 6465-03-8 N-(4-aminophenyl)carbamic acid methyl ester 

Relevant articles and documents

Synthesis of alkyl N-(C-nitrosoaryl)carbamates and some reactions thereof

Reactions of alkyl N-phenylcarbamates, m-di(methoxycarboxyamido)benzene, and methyl N-(o-tolyl)carbamate with nitrosylsulfuric acid in glacial acetic acid afford N-(C-nitrosoaryl)carbamates; under these conditions tert-bulyl N-phenylcarbamate suffers decarboxylation, methyl N-(p-tolyl)-, methyl N-(p-methoxyphenyl)carbamates, o-and p-di(methoxycarboxyamido)benzenes are nitrated, and isomeric methyl N-nitrophenylcarbamates and methyl N-(p-bromophenyl)carbamate do not react. The reduction of N-(C-nitrosoaryl)carbamates with dithionite afforded the corresponding aminocarbamates; the oxidation with nitric acid yielded carbamate nitro derivatives; the condensation with aniline and benzylpyridinium chloride resulted in carbamate derivatives of azobenzene and phenylnitron.